Archives des mots-clés : research data

Data Sharing: Convert Challenges into Opportunities

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Author : Ana Sofia Figueiredo

Initiatives for sharing research data are opportunities to increase the pace of knowledge discovery and scientific progress. The reuse of research data has the potential to avoid the duplication of data sets and to bring new views from multiple analysis of the same data set.

For example, the study of genomic variations associated with cancer profits from the universal collection of such data and helps in selecting the most appropriate therapy for a specific patient. However, data sharing poses challenges to the scientific community.

These challenges are of ethical, cultural, legal, financial, or technical nature. This article reviews the impact that data sharing has in science and society and presents guidelines to improve the efficient sharing of research data.

URL : Data Sharing: Convert Challenges into Opportunities

DOI : https://doi.org/10.3389/fpubh.2017.00327

Balancing the local and the universal in maintaining ethical access to a genomics biobank

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Authors : Catherine Heeney, Shona M. Kerr

Background

Issues of balancing data accessibility with ethical considerations and governance of a genomics research biobank, Generation Scotland, are explored within the evolving policy landscape of the past ten years. During this time data sharing and open data access have become increasingly important topics in biomedical research.

Decisions around data access are influenced by local arrangements for governance and practices such as linkage to health records, and the global through policies for biobanking and the sharing of data with large-scale biomedical research data resources and consortia.

Methods

We use a literature review of policy relevant documents which apply to the conduct of biobanks in two areas: support for open access and the protection of data subjects and researchers managing a bioresource.

We present examples of decision making within a biobank based upon observations of the Generation Scotland Access Committee. We reflect upon how the drive towards open access raises ethical dilemmas for established biorepositories containing data and samples from human subjects.

Results

Despite much discussion in science policy literature about standardisation, the contextual aspects of biobanking are often overlooked. Using our engagement with GS we demonstrate the importance of local arrangements in the creation of a responsive ethical approach to biorepository governance.

We argue that governance decisions regarding access to the biobank are intertwined with considerations about maintenance and viability at the local level. We show that in addition to the focus upon ever more universal and standardised practices, the local expertise gained in the management of such repositories must be supported.

Conclusions

A commitment to open access in genomics research has found almost universal backing in science and health policy circles, but repositories of data and samples from human subjects may have to operate under managed access, to protect privacy, align with participant consent and ensure that the resource can be managed in a sustainable way.

Data access committees need to be reflexive and flexible, to cope with changing technology and opportunities and threats from the wider data sharing environment. To understand these interactions also involves nurturing what is particular about the biobank in its local context.

URL : Balancing the local and the universal in maintaining ethical access to a genomics biobank

DOI : https://doi.org/10.1186/s12910-017-0240-7

Assessing Research Data Deposits and Usage Statistics within IDEALS

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Author : Christie A. Wiley

Objectives

This study follows up on previous work that began examining data deposited in an institutional repository. The work here extends the earlier study by answering the following lines of research questions: (1) What is the file composition of datasets ingested into the University of Illinois at Urbana-Champaign (UIUC) campus repository? Are datasets more likely to be single-file or multiple-file items? (2) What is the usage data associated with these datasets? Which items are most popular?

Methods

The dataset records collected in this study were identified by filtering item types categorized as “data” or “dataset” using the advanced search function in IDEALS. Returned search results were collected in an Excel spreadsheet to include data such as the Handle identifier, date ingested, file formats, composition code, and the download count from the item’s statistics report.

The Handle identifier represents the dataset record’s persistent identifier. Composition represents codes that categorize items as single or multiple file deposits. Date available represents the date the dataset record was published in the campus repository.

Download statistics were collected via a website link for each dataset record and indicates the number of times the dataset record has been downloaded. Once the data was collected, it was used to evaluate datasets deposited into IDEALS.

Results

A total of 522 datasets were identified for analysis covering the period between January 2007 and August 2016. This study revealed two influxes occurring during the period of 2008-2009 and in 2014. During the first timeframe a large number of PDFs were deposited by the Illinois Department of Agriculture.

Whereas, Microsoft Excel files were deposited in 2014 by the Rare Books and Manuscript Library. Single-file datasets clearly dominate the deposits in the campus repository. The total download count for all datasets was 139,663 and the average downloads per month per file across all datasets averaged 3.2.

Conclusion

Academic librarians, repository managers, and research data services staff can use the results presented here to anticipate the nature of research data that may be deposited within institutional repositories.

With increased awareness, content recruitment, and improvements, IRs can provide a viable cyberinfrastructure for researchers to deposit data, but much can be learned from the data already deposited.

Awareness of trends can help librarians facilitate discussions with researchers about research data deposits as well as better tailor their services to address short-term and long-term research needs.

URL : Assessing Research Data Deposits and Usage Statistics within IDEALS

DOI : https://doi.org/10.7191/jeslib.2017.1112

Documentation and Visualisation of Workflows for Effective Communication, Collaboration and Publication @ Source

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Authors : Cerys Willoughby, Jeremy G. Frey

Workflows processing data from research activities and driving in silico experiments are becoming an increasingly important method for conducting scientific research. Workflows have the advantage that not only can they be automated and used to process data repeatedly, but they can also be reused – in part or whole – enabling them to be evolved for use in new experiments.

A number of studies have investigated strategies for storing and sharing workflows for the benefit of reuse. These have revealed that simply storing workflows in repositories without additional context does not enable workflows to be successfully reused.

These studies have investigated what additional resources are needed to facilitate users of workflows and in particular to add provenance traces and to make workflows and their resources machine-readable.

These additions also include adding metadata for curation, annotations for comprehension, and including data sets to provide additional context to the workflow. Ultimately though, these mechanisms still rely on researchers having access to the software to view and run the workflows.

We argue that there are situations where researchers may want to understand a workflow that goes beyond what provenance traces provide and without having to run the workflow directly; there are many situations in which it can be difficult or impossible to run the original workflow.

To that end, we have investigated the creation of an interactive workflow visualization that captures the flow chart element of the workflow with additional context including annotations, descriptions, parameters, metadata and input, intermediate, and results data that can be added to the record of a workflow experiment to enhance both curation and add value to enable reuse.

We have created interactive workflow visualisations for the popular workflow creation tool KNIME, which does not provide users with an in-built function to extract provenance information that can otherwise only be viewed through the tool itself.

Making use of the strengths of KNIME for adding documentation and user-defined metadata we can extract and create a visualisation and curation package that encourages and enhances curation@source, facilitating effective communication, collaboration, and reuse of workflows.

URL : Documentation and Visualisation of Workflows for Effective Communication, Collaboration and Publication @ Source

DOI : https://doi.org/10.2218/ijdc.v12i1.532

Research Transparency: A Preliminary Study of Disciplinary Conceptualisation, Drivers, Tools and Support Services

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Authors : Liz Lyon, Wei Jeng, Eleanor Mattern

This paper describes a preliminary study of research transparency, which draws on the findings from four focus group sessions with faculty in chemistry, law, urban and social studies, and civil and environmental engineering.

The multi-faceted nature of transparency is highlighted by the broad ways in which the faculty conceptualised the concept (data sharing, ethics, replicability) and the vocabulary they used with common core terms identified (data, methods, full disclosure).

The associated concepts of reproducibility and trust are noted. The research lifecycle stages are used as a foundation to identify the action verbs and software tools associated with transparency.

A range of transparency drivers and motivations are listed. The role of libraries and data scientists is discussed in the context of the provision of transparency services for researchers.

URL : Research Transparency: A Preliminary Study of Disciplinary Conceptualisation, Drivers, Tools and Support Services

DOI : https://doi.org/10.2218/ijdc.v12i1.530

Amplifying Data Curation Efforts to Improve the Quality of Life Science Data

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Authors : Mariam Alqasab, Suzanne M. Embury, Sandra de F. Mendes Sampaio

In the era of data science, datasets are shared widely and used for many purposes unforeseen by the original creators of the data. In this context, defects in datasets can have far reaching consequences, spreading from dataset to dataset, and affecting the consumers of data in ways that are hard to predict or quantify.

Some form of waste is often the result. For example, scientists using defective data to propose hypotheses for experimentation may waste their limited wet lab resources chasing the wrong experimental targets. Scarce drug trial resources may be used to test drugs that actually have little chance of giving a cure.

Because of the potential real world costs, database owners care about providing high quality data. Automated curation tools can be used to an extent to discover and correct some forms of defect.

However, in some areas human curation, performed by highly-trained domain experts, is needed to ensure that the data represents our current interpretation of reality accurately.

Human curators are expensive, and there is far more curation work to be done than there are curators available to perform it. Tools and techniques are needed to enable the full value to be obtained from the curation effort currently available.

In this paper,we explore one possible approach to maximising the value obtained from human curators, by automatically extracting information about data defects and corrections from the work that the curators do.

This information is packaged in a source independent form, to allow it to be used by the owners of other databases (for which human curation effort is not available or is insufficient).

This amplifies the efforts of the human curators, allowing their work to be applied to other sources, without requiring any additional effort or change in their processes or tool sets. We show that this approach can discover significant numbers of defects, which can also be found in other sources.

URL : Amplifying Data Curation Efforts to Improve the Quality of Life Science Data

DOI : https://doi.org/10.2218/ijdc.v12i1.495

Connecting Data Publication to the Research Workflow: A Preliminary Analysis

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Authors : Sünje Dallmeier-Tiessen, Varsha Khodiyar, Fiona Murphy, Amy Nurnberger, Lisa Raymond, Angus Whyte

The data curation community has long encouraged researchers to document collected research data during active stages of the research workflow, to provide robust metadata earlier, and support research data publication and preservation.

Data documentation with robust metadata is one of a number of steps in effective data publication. Data publication is the process of making digital research objects ‘FAIR’, i.e. findable, accessible, interoperable, and reusable; attributes increasingly expected by research communities, funders and society.

Research data publishing workflows are the means to that end. Currently, however, much published research data remains inconsistently and inadequately documented by researchers.

Documentation of data closer in time to data collection would help mitigate the high cost that repositories associate with the ingest process. More effective data publication and sharing should in principle result from early interactions between researchers and their selected data repository.

This paper describes a short study undertaken by members of the Research Data Alliance (RDA) and World Data System (WDS) working group on Publishing Data Workflows. We present a collection of recent examples of data publication workflows that connect data repositories and publishing platforms with research activity ‘upstream’ of the ingest process.

We re-articulate previous recommendations of the working group, to account for the varied upstream service components and platforms that support the flow of contextual and provenance information downstream.

These workflows should be open and loosely coupled to support interoperability, including with preservation and publication environments. Our recommendations aim to stimulate further work on researchers’ views of data publishing and the extent to which available services and infrastructure facilitate the publication of FAIR data.

We also aim to stimulate further dialogue about, and definition of, the roles and responsibilities of research data services and platform providers for the ‘FAIRness’ of research data publication workflows themselves.

URL : Connecting Data Publication to the Research Workflow: A Preliminary Analysis

DOI : https://doi.org/10.2218/ijdc.v12i1.533