Comparison of Study Results Reported in medRxiv Preprints vs Peer-reviewed Journal Articles

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Authors : Guneet Janda, Vishal Khetpal, Xiaoting Shi, Joseph S. Ross, Joshua D. Wallach

Question

What is the concordance among sample size, primary end points, results for primary end points, and interpretations described in preprints of clinical studies posted on medRxiv that are subsequently published in peer-reviewed journals (preprint-journal article pairs)?

Findings

In this cross-sectional study of 547 clinical studies that were initially posted to medRxiv and later published in peer-reviewed journals, 86.4% of preprint-journal article pairs were concordant in terms of sample size, 97.6% in terms of primary end points, 81.1% in terms of results of primary end points, and 96.2% in terms of study interpretations.

Meaning

This study suggests that most clinical studies posted as preprints on medRxiv and subsequently published in peer-reviewed journals had concordant study characteristics, results, and final interpretations.

URL : Comparison of Clinical Study Results Reported in medRxiv Preprints vs Peer-reviewed Journal Articles

Original location : https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2799350

Phase 1 of the NIH Preprint Pilot: Testing the viability of making preprints discoverable in PubMed Central and PubMed

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Authors : Kathryn Funk, Teresa Zayas-Cabán, Jeffrey Beck

Introduction

The National Library of Medicine (NLM) launched a pilot in June 2020 to 1) explore the feasibility and utility of adding preprints to PubMed Central (PMC) and making them discoverable in PubMed and 2) to support accelerated discoverability of NIH-supported research without compromising user trust in NLM’s widely used literature services.

Methods

The first phase of the Pilot focused on archiving preprints reporting NIH-supported SARS-CoV-2 virus and COVID-19 research. To launch Phase 1, NLM identified eligible preprint servers and developed processes for identifying NIH-supported preprints within scope in these servers.

Processes were also developed for the ingest and conversion of preprints in PMC and to send corresponding records to PubMed. User interfaces were modified for display of preprint records. NLM collected data on the preprints ingested and discovery of preprint records in PMC and PubMed and engaged users through focus groups and a survey to obtain direct feedback on the Pilot and perceptions of preprints.

Results

Between June 2020 and June 2022, NLM added more than 3,300 preprint records to PMC and PubMed, which were viewed 4 million times and 3 million times, respectively. Nearly a quarter of preprints in the Pilot were not associated with a peer-reviewed published journal article. User feedback revealed that the inclusion of preprints did not have a notable impact on trust in PMC or PubMed.

Discussion

NIH-supported preprints can be identified and added to PMC and PubMed without disrupting existing operations processes. Additionally, inclusion of preprints in PMC and PubMed accelerates discovery of NIH research without reducing trust in NLM literature services.

Phase 1 of the Pilot provided a useful testbed for studying NIH investigator preprint posting practices, as well as knowledge gaps among user groups, during the COVID-19 public health emergency, an unusual time with heightened interest in immediate access to research results.

DOI : https://doi.org/10.1101/2022.12.12.520156

La science (dé)confinée

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Autrice/Author : Clara Galliano

Plusieurs pays d’Asie, d’Afrique, d’Europe, d’Amérique latine et certains états américains ont mis en place des mesures de confinement pour lutter contre la propagation du virus et l’arrivée de nouveaux variants.

En France comme ailleurs, ces mesures ont provoqué de lourdes conséquences sur l’économie du pays, ainsi que sur le moral des populations. Cet article propose d’évaluer, à partir de plusieurs méthodes, les impacts du confinement sur la recherche en étudiant plusieurs éléments comme : les collaborations internationales, les efforts des éditeurs sur l’accessibilité aux ressources numériques et les différentes enquêtes menées au sein des communautés scientifiques.

La Science Ouverte, entre mouvement et norme, a été un point clé stratégique et libérateur pendant la crise sanitaire afin d’accéder aux résultats pour faire avancer les recherches sur le vaccin, mais aussi pour continuer à maintenir l’activité scientifique quand tout la contraignait.

URL : https://revue-cossi.numerev.com/articles/revue-11/2750-la-science-deconfinee

Open access and predatory publishing: a survey of the publishing practices of academic pharmacists and nurses in the United States

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Authors : Bridget C. Conlogue, Neyda V. Gilman, Louisa M. Holmes

Objective: Academics are under great pressure to publish their research, the rewards for which are well known (tenure, promotion, grant funding, professional prestige). As open access publishing gains acceptance as a publishing option, researchers may choose a “predatory publisher.” The purpose of this study is to investigate the motivations and rationale of pharmacy and nursing academics in the United States to publish in open access journals that may be considered “predatory.”

Methods: A 26-item questionnaire was programmed in Qualtrics and distributed electronically to approximately 4,500 academic pharmacists and nurses, 347 of whom completed questionnaires (~8%). Pairwise correlations were performed followed by a logistic regression to evaluate statistical associations between participant characteristics and whether participants had ever paid an article processing fee (APF).

Results: Participants who had published more articles, were more familiar with predatory publishing, and who were more concerned about research metrics and tenure were more likely to have published in open access journals. Moderate to high institutional research intensity has an impact on the likelihood of publishing open access. The majority of participants who acknowledged they had published in a predatory journal took no action after realizing the journal was predatory and reported no negative impact on their career for having done so.

Conclusion: The results of this study provide data and insight into publication decisions made by pharmacy and nursing academics. Gaining a better understanding of who publishes in predatory journals and why can help address the problems associated with predatory publishing at the root.

URL : Open access and predatory publishing: a survey of the publishing practices of academic pharmacists and nurses in the United States

DOI : https://doi.org/10.5195/jmla.2022.1377

Champions of Transparency in Education: What Journal Reviewers Can Do to Encourage Open Science Practices

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Authors : Rachel Renbarger, Jill L. Adelson, Joshua Rosenberg, Sondra M Stegenga, Olivia Lowrey, Pamela Rose Buckley, Qiyang Zhang

As the field of education and especially gifted education gradually moves towards open science, our research community increasingly values transparency and openness brought by open science practices.

Yet, individual researchers may be reluctant to adopt open science practices due to low incentives, barriers of extra workload, or lack of support to apply these in certain areas, such as qualitative research.

We encourage and give guidelines to reviewers to champion open science practices by warmly influencing authors to consider applying open science practices to quantitative, qualitative, and mixed methods research and providing ample support to produce higher-quality publications.

Instead of imposing open science practices on authors, we advocate reviewers suggest small, non-threatening, specific steps to support authors without making them feel overwhelmed, judged, or punished.

We believe that these small steps taken by reviewers will make a difference to create a more supportive environment for researchers to adopt better practices.

DOI : https://doi.org/10.35542/osf.io/xqfwb

An Open Social Scholarship Path for the Humanities

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Authors : Alyssa Arbuckle, Ray Siemens, Jon Bath, Constance Crompton, Laura Estill, Tanja Niemann, Jon Saklofkse, Lynne Siemens

Open digital scholarship is significant for facilitating public access to and engagement with research, and as a foundation for growing digital scholarly infrastructure around the world today and in the future. But the path to adopting open, digital scholarship on a national—never mind international—scale is challenged by several real, pragmatic issues. In this article, we consider these issues as well as proactive strategies for the realization of robust, inclusive, publicly engaged, open scholarship in digital form.

We draw on the INKE Partnership’s central goal of fostering open social scholarship (academic practice that enables the creation, dissemination, and engagement of open research by specialists and non-specialists in accessible and significant ways).

In doing so, we look to pursue more open, and more social, scholarly activities through knowledge mobilization, community training, public engagement, and policy recommendations in order to understand and address challenges facing digital scholarly communication.

We then provide tangible details, outlining how the INKE Partnership puts open social scholarship theory into practice, with an eye to a more open and engaged future.

URL : An Open Social Scholarship Path for the Humanities

DOI : https://doi.org/10.3998/jep.1973

An iterative and interdisciplinary categorisation process towards FAIRer digital resources for sensitive life-sciences data

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Authors : Romain David, Christian Ohmann, Jan‑Willem Boiten, Mónica Cano Abadía, Florence Bietrix, Steve Canham, Maria Luisa Chiusano, Walter Dastrù, Arnaud Laroquette, Dario Longo, Michaela Th. Mayrhofer, Maria Panagiotopoulou, Audrey S. Richard, Sergey Goryanin, Pablo Emilio Verde

For life science infrastructures, sensitive data generate an additional layer of complexity. Cross-domain categorisation and discovery of digital resources related to sensitive data presents major interoperability challenges. To support this FAIRification process, a toolbox demonstrator aiming at support for discovery of digital objects related to sensitive data (e.g., regulations, guidelines, best practice, tools) has been developed.

The toolbox is based upon a categorisation system developed and harmonised across a cluster of 6 life science research infrastructures. Three different versions were built, tested by subsequent pilot studies, finally leading to a system with 7 main categories (sensitive data type, resource type, research field, data type, stage in data sharing life cycle, geographical scope, specific topics).

109 resources attached with the tags in pilot study 3 were used as the initial content for the toolbox demonstrator, a software tool allowing searching of digital objects linked to sensitive data with filtering based upon the categorisation system.

Important next steps are a broad evaluation of the usability and user-friendliness of the toolbox, extension to more resources, broader adoption by different life-science communities, and a long-term vision for maintenance and sustainability.

URL : An iterative and interdisciplinary categorisation process towards FAIRer digital resources for sensitive life-sciences data

DOI : https://doi.org/10.1038/s41598-022-25278-z