Open Access Target Validation Is a More Efficient Way to Accelerate Drug Discovery

« There is a scarcity of novel treatments to address many unmet medical needs. Industry and academia are finally coming to terms with the fact that the prevalent models and incentives for innovation in early stage drug discovery are failing to promote progress quickly enough. Here we will examine how an open model of precompetitive public–private research partnership is enabling efficient derisking and acceleration in the early stages of drug discovery, whilst also widening the range of communities participating in the process, such as patient and disease foundations. »

URL : Open Access Target Validation Is a More Efficient Way to Accelerate Drug Discover

DOI: 10.1371/journal.pbio.1002164

E-book publishing in Lithuania: the publisher‘s perspective

« Introduction. The aim of the research was to increase understanding of the state of e-book production in Lithuania and collect the data about the opinions of publishers regarding the future of e-books in the country.

Method. A review of similar surveys in other countries was carried out and the research method was based on Winston’s model of innovation diffusion. The questionnaire to publishers was prepared using the models of book publishing and distribution or book circuit developed by Murray and Squires. Data were collected by surveying respondents using paper and online questionnaires.

Analysis. A quantitative descriptive statistical analysis was carried out, while open questions were analysed qualitatively looking for emerging topics.

Results. More than half of active Lithuanian publishers completed the survey. Thirty per cent of those who answered the questionnaire publish e-books, but only six publishers had published a significant number of titles. The overall perception of other actors of the book market, such as libraries, book-sellers and self-publishing authors and others is positive. They are not regarded as a threat. The publishers do not expect rapid and significant growth of e-book market in Lithuania in the near future.

Conclusions. The biggest hindrance to growth is a small size of the market and the lack of an export market for Lithuanian e-books. The demand of users for portable and convenient format and the use of new technologies in the educational system are the two biggest drivers in the development of e-book production. The user preference for traditional printed book is seen as one of the barriers for further development. Lithuanian publishers regard the market of e-books as rather uncertain and do not risk high investments in it. »

URL : http://www.informationr.net/ir/20-2/paper672.html

Social construction of knowledge in Wikipedia

« This paper investigates how knowledge is constructed collaboratively in a crowd-sourced environment. More specifically, the study presented in this paper empirically analyzes online discussions in regard to Wikipedia entries on the Fukushima Nuclear Power Plant Disaster that occurred in March 2011 in Japan. For this study, we examined the encyclopedia articles in both the English and Japanese versions of Wikipedia. The findings indicate similarities and differences between the two language versions. The implications of the study for collaborative knowledge production are also discussed. »

URL : http://dx.doi.org/10.5210/fm.v20i6.5869

E-books: Histories, trajectories, futures

« This essay traces the historical trajectory of e-books in the U.S. and imagines their possible futures. Legal, economic, and technical developments that led to contemporary e-books reveal a tension between commercial and non-commercial programming. Commercial e-book designs control end uses, reduce production and distribution costs, stimulate consumption, and monitor user behaviors; however, alternative producers and users on the periphery continue to challenge these centralizing tendencies. »

URL : http://dx.doi.org/10.5210/fm.v20i6.5641

Presse et numérique – L’invention d’un nouvel écosystème

« La presse écrite et l’édition numérique d’information sont au coeur de la mutation des moyens de communication. Le rapport dresse un panorama du nouveau paysage de la presse, analyse les nouveaux métiers de la presse, présente les nouveaux acteurs (informaticiens, codeurs, graphistes, designers, spécialistes du Data…) et propose un état des lieux du secteur pour permettre aux acteurs politiques de mieux cibler leurs interventions. »

URL : http://www.ladocumentationfrancaise.fr/rapports-publics/154000368-presse-et-numerique-l-invention-d-un-nouvel-ecosysteme

Evolution or revolution? Publishers’ perceptions of future directions in research communications and the publisher role

« This report presents a snapshot of the views of a wide range of publishers, covering their perceptions of future directions in research communications, scholarly publishing and the role of publishers. It is important to emphasise that there is not a single “publishers’ view” on these matters: the publishers represented here are of differing scale, ownership, (dominant) business model, discipline, and tradition, and their views reflect that diversity of experience.

 Nearly 20 publishers of different types and scale were interviewed: for-profit and not-for-profit; open access and subscription-based; commercial, society, university presses; and with representation from all scholarly fields. We aimed to synthesise the views thus gathered, while reflecting the diversity of opinion where salient. »

 URL : Evolution or revolution? Publishers’ perceptions of future directions in research communications and the publisher role

Related URL : http://www.rcuk.ac.uk/RCUK-prod/assets/documents/international/EvolutionOrRevolution.pdf

The use of open resources among highly cited young Ukrainian scientists

« There are scientific and educational institutions in Ukraine which actively introduce and fill up open sources in web to make integration of Ukrainian scientists into worldwide communication more effective. Ukrainian scientists’ citation boost with their complete works available at open sources must indicate the success of such integration. This article, grounding in Scopus and Google Scholar data, investigates the types of scientific web-sources used by Ukrainian scientists for promotion of their works. »

URL : http://eprints.rclis.org/25210/